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Colombia: Cali, Popayán and Florencia + 2 more

A road trip through Cali, Popayán and Florencia + 2 more, 5 stops in Colombia.

Cali is a sprawling city in Valle del Cauca Department, Colombia, recognised as a UNESCO World Heritage site. Popayán sits at 1,760 metres in Colombia's Cauca Department, a city where colonial architecture and modern life coexist on steep Andean slopes. Florencia is a regional hub in Caquetá Department, southern Colombia, serving as a practical base for exploring the country's Amazon-adjacent interior. Quibdó is the capital of Chocó Department in Colombia, a city of over 129,000 people with a distinctive character shaped by its regional setting.

Why it works

Rather than one city, this threads Cali, Popayán and Florencia and more into a single trip, so you see more of Colombia in one go. Spend longest wherever suits you.

The route

1CaliDrive2PopayánDrive3FlorenciaDrive4QuibdóDrive5Montería
Explore this journey — start at Cali →

Your itinerary

  1. 1Cali1–2 nights
    🧭 Tours & experiences via Klook🛏 Accommodation via Expedia✈ Flights via Aviasales
    🎟 Tickets🚆 Trains🚗 Car hire🚕 Transfer📶 eSIMinsurance
  2. 🚗 Drive Cali → PopayánFind car hire in Popayán via EconomyBookings
    2Popayán1–2 nights
    🧭 Tours & experiences via Klook🛏 Accommodation via Expedia✈ Flights via Aviasales
    🎟 Tickets🚆 Trains🚗 Car hire🚕 Transfer📶 eSIMinsurance
  3. 🚗 Drive Popayán → FlorenciaFind car hire in Florencia via EconomyBookings
    3Florencia1–2 nights
    🧭 Tours & experiences via Klook🛏 Accommodation via Expedia✈ Flights via Aviasales
    🎟 Tickets🚆 Trains🚗 Car hire🚕 Transfer📶 eSIMinsurance
  4. 🚗 Drive Florencia → QuibdóFind car hire in Quibdó via EconomyBookings
    4Quibdó1–2 nights
    🧭 Tours & experiences via Klook🛏 Accommodation via Expedia✈ Flights via Aviasales
    🎟 Tickets🚆 Trains🚗 Car hire🚕 Transfer📶 eSIMinsurance
  5. 🚗 Drive Quibdó → MonteríaFind car hire in Montería via EconomyBookings
    5Montería1–2 nights
    🧭 Tours & experiences via Klook🛏 Accommodation via Expedia✈ Flights via Aviasales
    🎟 Tickets🚆 Trains🚗 Car hire🚕 Transfer📶 eSIMinsurance

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Make it yours

Plan each destination

Cali travel guidePopayán travel guideFlorencia travel guideQuibdó travel guideMontería travel guideMore Colombia itineraries

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