Cuba: Santiago de Cuba, Guantánamo and Holguín + 2 more
A multi-city trip through Santiago de Cuba, Guantánamo and Holguín + 2 more, 5 stops in Cuba.
- City & culture
- 10–15 days
- Balanced pace
Santiago de Cuba is the island's second-largest city and a place where historical significance and cultural richness intersect at every turn. Guantánamo is a city of historical weight in Cuba's eastern reaches, recognised as a UNESCO World Heritage site. Holguín is a city in eastern Cuba with a population of around 319,000, serving as a significant hub in Holguín Province. Bayamo is a city of historical weight in Cuba's eastern reaches, capital of Granma Province.
Why it works
Rather than one city, this threads Santiago de Cuba, Guantánamo and Holguín and more into a single trip, so you see more of Cuba in one go. Spend longest wherever suits you.
The route
Explore this journey — start at Santiago de Cuba →Your itinerary
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🚗 Drive Santiago de Cuba → Guantánamo
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🚗 Drive Guantánamo → Holguín
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🚗 Drive Holguín → Bayamo
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🚗 Drive Bayamo → Las Tunas
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Make it yours
- Spend more time in Santiago de Cuba
- Trim to just Santiago de Cuba and Guantánamo for a shorter trip
- Add a neighbouring stop from the Cuba guide