| Gran Sasso e Monti della Laga National Park Italian national park
| 148,935 km² | — |
| Matese National Park National park in Italy
| 87,900 km² | Naples
|
| Gran Paradiso National Park Italian national park
| 71,040 km² | Turin
|
| Sibillini Mountains National Park Protected area
| 69,722 km² | Bastia umbra
|
| Maiella National Park Italian national park
| 62,838 km² | — |
| Stelvio National Park National park in Italy
| 59,741 km² | The Alps
|
| Appennino Tosco-Emiliano National Park National park in Italy
| 22,793 km² | — |
| Dolomiti Bellunesi National Park National park of Italy
| 15,030 km² | — |
| Pantelleria National Park National park in Italy
| 6,640 km² | — |
| Pollino National Park National park in Italy
| 1,925 km² | — |
| Cilento, Vallo di Diano and Alburni National Park Italian national park
| 1,811 km² | Agropoli
|
| Gargano National Park National park of Italy
| 1,181 km² | — |
| Arcipelago Toscano National Park National park
| 792 km² | — |
| Gennargentu National Park National park in Sardinia
| 739 km² | — |
| Sila National Park National park
| 737 km² | — |
| Appennino Lucano - Val d'Agri - Lagonegrese National Park National park in Italy
| 690 km² | — |
| Alta Murgia National Park National park in Apulia, southern Italy
| 680 km² | Gravina in Puglia
|
| Aspromonte National Park National park
| 642 km² | — |
| Abruzzo, Lazio and Molise National Park Italian national park
| 497 km² | — |
| Foreste Casentinesi, Monte Falterona, Campigna National Park Italian national park
| 368 km² | Arezzo
|
| Arcipelago di La Maddalena National Park National park
| 201 km² | Olbia
|
| Vesuvius National Park National park in Italy
| 73 km² | Poggiomarino
|
| Circeo National Park National park in Italy
| 56 km² | — |
| Asinara National Park National park
| 52 km² | — |
| Cinque Terre National Park National park in Italy
| 39 km² | — |
| Val Grande National Park National park in Italy
| 17 km² | — |